What is the simvastatina?

La simvastatina se utiliza junto con la dieta, pérdida de peso y ejercicio para reducir el riesgo de infarto y derrame cerebral y para reducir la probabilidad de que se necesite una cirugía de corazón en las personas que tienen una enfermedad cardíaca o que estén en riesgo de desarrollar una.

What should I do if I have a simvastatina?

La simvastatina puede ocasionar efectos secundarios. Informe a su médico si alguno de estos síntomas es grave o no desaparece: Algunos efectos secundarios pueden ser graves. Si experimenta cualquiera de los síntomas siguientes, llame a su médico inmediatamente o busque tratamiento médico de emergencia.

What are the side effects of simvastatin?

It can raise triglyceride levels and may increase your risk of liver damage. Get emergency medical help if you have any of these signs of an allergic reaction to simvastatin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Is simvastatin soluble in water?

It is a white, nonhygroscopic, crystalline powder that is practically insoluble in water, and freely soluble in chloroform, methanol, and ethanol . Simvastatin is an effective serum lipid -lowering drug that can decrease low density lipoprotein (LDL) levels by up to 50%.

What type of drug is simvastatin?

Simvastatin is in a group of drugs called HMG CoA reductase inhibitors, or statins.. It reduces levels of bad cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of good cholesterol (high-density lipoprotein, or HDL). Simvastatin is used to lower cholesterol...

How is simvastatin exposed to the general population?

The general population may be exposed to simvastatin via ingestion of pharmaceutical products containing simvastatin. (SRC) Simvastatins production and use as an antilipemic (1) may result in its release to the environment through various waste streams (SRC).

When was simvastatin Last updated?

Last updated on Nov 2, 2020. What is simvastatin? Simvastatin belongs to a group of drugs called HMG CoA reductase inhibitors, or statins.

What is the half life of simvastatin?

Simvastatin is a prodrug activated by first-pass hepatic metabolism to a hydroxyacid metabolite, which has a half-life of 1–2 hours. Simvastatin is used to control hypercholesterolemia.

No, theres no evidence that simvastatin is addictive. You wont get any withdrawal symptoms when you stop taking it. What will happen if I come off it? You may want to stop simvastatin if you think youre having side effects. Talk to your doctor first to see if it really is a side effect of simvastatin or an unrelated problem.

Can I take simvastatin If I am pregnant or breastfeeding?

What are the side effects of simvastatin 20 mg?

Side effects of simvastatin 20 mg. Patients using simvastatin are likely to experience headache, nausea and vomiting, stomack pain, diarrhea, and sometimes muscle pain. There is a possibility for some allergic reactions to simvastatin, too. The drug may damage the liver, being the reason for liver tests before and during the use of simvastatin.

Does simvastatin cause muscle pain as a side effect?

Its thought that simvastatin (Zocor) may be more likely to cause muscle pain as a side effect than other statins when its taken at high doses.

What are the side effects of simvastatin and Zocor?

The most common side effects of simvastatin are: abnormal liver tests. Other side effects include: memory impairment. What are the more serious side effects of Zocor? The most serious potential side effects are liver damage and muscle inflammation or breakdown.

What are the possible complications of simvastatin toxicity?

Simvastatin has been associated with rare cases of severe myopathy and rhabdomyolysis. This is accompanied by elevations in creatine kinase, myoglobinuria, and proteinuria, as well as renal failure.

Atorvastatin is lipid soluble statin. Then I tried with Pravastatin (which is a water soluble statin), but still here also no success. Can anyone suggest me some ideas or have any experience ?

Does solubility enhance the bioavailability of simvastatin in GI media?

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